Drug interactions with grape- 1997;33:103-21
The most documented products in terms of reported interactions are: Hypericum perforatum (St
Digoxin disease interactions There are 13 disease interactions with digoxin which include: accessory AV pathway
Fludrocortisone is classified as belonging to the following category: P-Glycoprotein Substrates
Grapefruit and constituents were examined for decreased MDR1-mediated digoxin or vinblastine efflux
Major Likelihood of Occurrence Likely Well-controlled human studies have demonstrated the likely existence of this interaction References Lilja JJ, Kivisto KT
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Includes information on severity of
These include: simvastatin, buspirone, felodipine, and possibly cyclosporine
Before taking dilTIAZem, tell your doctor if you also use digoxin
In extreme cases, this may lead to rhabdomyolysis and even death, but this is rare
The use of grapefruit juice with a few specific drugs (eg, fexofenadine, digoxin) may lower plasma drug concentrations by inhibiting drug absorption catalyzed by the organic It should also be noted that grapefruit juice, an intestinal P-gp inhibitor, has a non-significant effect on digoxin serum concentrations 6, and ketoconazole — a potent P-gp inhibitor — is not The clinical significance of any pharmacokinetic interactions is unclear
Interaction Details
No interactions have been reported or no interaction data is currently available
Theoretically, it might inhibit intestinal P-gp, but evidence is conflicting
Colchicine is classified as belonging to the following category: Colchicine
The interaction between grapefruit and calcium channel blockers is strongest, for example, with felodipine (Plendil), nicardipine (Cardene), and nisoldipine (Sular) and The chemicals in grapefruit can cause your body to absorb either too much or too little medicine into your bloodstream
Grapefruit juice can increase levels of drugs metabolized by CYP3A4
Examples of CYP3A4 inhibitors include grapefruit, diltiazem, digoxin, and many HIV medications